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From DNA Damage & Stress Signalling to Cell Death Poly ADP-Ribosylation Reaction

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[PDF.lz13] From DNA Damage & Stress Signalling to Cell Death Poly ADP-Ribosylation Reaction

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 | #9348584 in Books |  2000-12-15 | Original language:English | PDF # 1 |  6.10 x.90 x9.00l,1.33 | File type: PDF | 238 pages

|| ||"From DNA Damage and Stress Signalling to Cell Death: Poly(ADP-ribosyl)ation Reactions is the first monograph fully dedicated to the discussion of the biochemistry, molecular biology and molecular genetics of protein-poly(ADP-ribosyl)ation reactions.

Poly-ADP ribosylation reactions govern some of the fundamental processes of life. PARP 1 is a highly conserved enzyme and a constitutive factor of the DNA damage surveillance network and plays an essential role in the protection and processing of DNA ends as they arise in DNA damage, repair, and recombination. The recent discovery of multiple members of the PARP family suggests an expanded role for poly-ADP ribosylation reactions. This book contains the basic knowledge o...

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